NLRP4 FISH Probe
The NLRP4 FISH probe is designed to hybridize to the NLRP4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| NLRP4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| NLRP4-20-RE | 20 (40 μL) | 200 μL |  |
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| NLRP4-20-GO | 20 (40 μL) | 200 μL |  |
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| NLRP4-20-GR | 20 (40 μL) | 200 μL |  |
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| NLRP4-20-AQ | 20 (40 μL) | 200 μL |  |
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| NLRP4-20-DIG | 20 (40 μL) | 200 μL |  |
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| NLRP4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the nucleotide-binding and leucine-rich repeat receptor (NLR) family, and is predicted to contain an N-terminal pyrin effector domain (PYD), a centrally-located nucleotide-binding and oligomerization domain (NACHT) and C-terminal leucine-rich repeats (LRR). This gene product has a demonstrated role as a negative regulator of autophagy and type I interferon signaling pathways as a result of protein interactions with its NACHT domain. The PYD domain has also been shown to be important in the inhibition of NF-kB (nuclear factor kappa-light-chain-enhancer of activated B cells). [provided by RefSeq, Dec 2016]
Gene Details
Gene Symbol: NLRP4
Gene Name: NLR Family Pyrin Domain Containing 4
Chromosome: CHR19: 56347943-56393220
Locus: 19q13.43
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: NLRP4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: NLRP4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping