PDHB FISH Probe
The PDHB FISH probe is designed to hybridize to the PDHB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PDHB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PDHB-20-RE | 20 (40 μL) | 200 μL |  |
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| PDHB-20-GO | 20 (40 μL) | 200 μL |  |
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| PDHB-20-GR | 20 (40 μL) | 200 μL |  |
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| PDHB-20-AQ | 20 (40 μL) | 200 μL |  |
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| PDHB-20-DIG | 20 (40 μL) | 200 μL |  |
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| PDHB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and carbon dioxide, and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 beta subunit. Mutations in this gene are associated with pyruvate dehydrogenase E1-beta deficiency. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]
Gene Details
Gene Symbol: PDHB
Gene Name: Pyruvate Dehydrogenase E1 Beta Subunit
Chromosome: CHR3: 58413356-58419579
Locus: 3p14.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PDHB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PDHB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping