PLAT FISH Probe
The PLAT FISH probe is designed to hybridize to the PLAT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLAT-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PLAT-20-RE | 20 (40 μL) | 200 μL |  |
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| PLAT-20-GO | 20 (40 μL) | 200 μL |  |
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| PLAT-20-GR | 20 (40 μL) | 200 μL |  |
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| PLAT-20-AQ | 20 (40 μL) | 200 μL |  |
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| PLAT-20-DIG | 20 (40 μL) | 200 μL |  |
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| PLAT-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: PLAT
Gene Name: Plasminogen Activator, Tissue Type
Chromosome: CHR8: 42032235-42065194
Locus: 8p11.21
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PLAT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLAT-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping