PLOD2 FISH Probe
The PLOD2 FISH probe is designed to hybridize to the PLOD2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PLOD2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PLOD2-20-RE | 20 (40 μL) | 200 μL |  |
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| PLOD2-20-GO | 20 (40 μL) | 200 μL |  |
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| PLOD2-20-GR | 20 (40 μL) | 200 μL |  |
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| PLOD2-20-AQ | 20 (40 μL) | 200 μL |  |
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| PLOD2-20-DIG | 20 (40 μL) | 200 μL |  |
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| PLOD2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PLOD2
Gene Name: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2
Chromosome: CHR3: 145787227-145879282
Locus: 3q24
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: PLOD2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PLOD2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping