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PPP2R2B FISH Probe

The PPP2R2B FISH probe is designed to hybridize to the PPP2R2B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PPP2R2B-20-OR  (Standard Design) 20 (40 μL) 200 μL
PPP2R2B-20-RE 20 (40 μL) 200 μL
PPP2R2B-20-GO 20 (40 μL) 200 μL
PPP2R2B-20-GR 20 (40 μL) 200 μL
PPP2R2B-20-AQ 20 (40 μL) 200 μL
PPP2R2B-20-DIG 20 (40 μL) 200 μL
PPP2R2B-20-BIO 20 (40 μL) 200 μL

Gene Summary

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12. [provided by RefSeq, Jul 2016]

Gene Details

Gene Symbol: PPP2R2B

Gene Name: Protein Phosphatase 2 Regulatory Subunit Bbeta

Chromosome: CHR5: 145969067-146461033

Locus: 5q32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: PPP2R2B FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PPP2R2B-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping