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PRKAA2 FISH Probe

The PRKAA2 FISH probe is designed to hybridize to the PRKAA2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
PRKAA2-20-OR  (Standard Design) 20 (40 μL) 200 μL
PRKAA2-20-RE 20 (40 μL) 200 μL
PRKAA2-20-GO 20 (40 μL) 200 μL
PRKAA2-20-GR 20 (40 μL) 200 μL
PRKAA2-20-AQ 20 (40 μL) 200 μL
PRKAA2-20-DIG 20 (40 μL) 200 μL
PRKAA2-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: PRKAA2

Gene Name: Protein Kinase AMP-activated Catalytic Subunit Alpha 2

Chromosome: CHR1: 57110989-57181008

Locus: 1p32.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: PRKAA2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PRKAA2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping