SEARCH OUR PRODUCT CATALOG

As of April 10th, Empire is operating as an essential New York State business and has no production or shipping delays

PTAFR FISH Probe

The PTAFR FISH probe is designed to hybridize to the PTAFR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
PTAFR-20-OR  (Standard Design) 20 (40 μL) 200 μL
PTAFR-20-RE 20 (40 μL) 200 μL
PTAFR-20-GO 20 (40 μL) 200 μL
PTAFR-20-GR 20 (40 μL) 200 μL
PTAFR-20-AQ 20 (40 μL) 200 μL
PTAFR-20-DIG 20 (40 μL) 200 μL
PTAFR-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a seven-transmembrane G-protein-coupled receptor for platelet-activating factor (PAF) that localizes to lipid rafts and/or caveolae in the cell membrane. PAF (1-0-alkyl-2-acetyl-sn-glycero-3-phosphorylcholine) is a phospholipid that plays a significant role in oncogenic transformation, tumor growth, angiogenesis, metastasis, and pro-inflammatory processes. Binding of PAF to the PAF-receptor (PAFR) stimulates numerous signal transduction pathways including phospholipase C, D, A2, mitogen-activated protein kinases (MAPKs), and the phosphatidylinositol-calcium second messenger system. Following PAFR activation, cells become rapidly desensitized and this refractory state is dependent on PAFR phosphorylation, internalization, and down-regulation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]

Gene Details

Gene Symbol: PTAFR

Gene Name: Platelet Activating Factor Receptor

Chromosome: CHR1: 28473676-28520447

Locus: 1p35.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: PTAFR FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PTAFR-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping