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PTPN11 FISH Probe

The PTPN11 FISH probe is designed to hybridize to the PTPN11 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
PTPN11-20-OR  (Standard Design) 20 (40 μL) 200 μL
PTPN11-20-RE 20 (40 μL) 200 μL
PTPN11-20-GO 20 (40 μL) 200 μL
PTPN11-20-GR 20 (40 μL) 200 μL
PTPN11-20-AQ 20 (40 μL) 200 μL
PTPN11-20-DIG 20 (40 μL) 200 μL
PTPN11-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]

Gene Details

Gene Symbol: PTPN11

Gene Name: Protein Tyrosine Phosphatase, Non-receptor Type 11

Chromosome: CHR12: 112856535-112947717

Locus: 12q24.13

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: PTPN11 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: PTPN11-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping