RAD51 FISH Probe
The RAD51 FISH probe is designed to hybridize to the RAD51 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAD51-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RAD51-20-RE | 20 (40 μL) | 200 μL |  |
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| RAD51-20-GO | 20 (40 μL) | 200 μL |  |
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| RAD51-20-GR | 20 (40 μL) | 200 μL |  |
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| RAD51-20-AQ | 20 (40 μL) | 200 μL |  |
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| RAD51-20-DIG | 20 (40 μL) | 200 μL |  |
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| RAD51-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51, and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with the ssDNA-binding protein RPA and RAD52, and it is thought to play roles in homologous pairing and strand transfer of DNA. This protein is also found to interact with BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
Gene Details
Gene Symbol: RAD51
Gene Name: RAD51 Recombinase
Chromosome: CHR15: 40987326-41024356
Locus: 15q15.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RAD51 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RAD51-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping