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RAP1GAP FISH Probe

The RAP1GAP FISH probe is designed to hybridize to the RAP1GAP gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

SKU Test Kits Buffer Dye Color Order Now
RAP1GAP-20-OR  (Standard Design) 20 (40 μL) 200 μL
RAP1GAP-20-RE 20 (40 μL) 200 μL
RAP1GAP-20-GO 20 (40 μL) 200 μL
RAP1GAP-20-GR 20 (40 μL) 200 μL
RAP1GAP-20-AQ 20 (40 μL) 200 μL
RAP1GAP-20-DIG 20 (40 μL) 200 μL
RAP1GAP-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Aug 2011]

Gene Details

Gene Symbol: RAP1GAP

Gene Name: RAP1 GTPase Activating Protein

Chromosome: CHR1: 21922707-21995856

Locus: 1p36.12

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Scientific Citations

There are currently no FISH related citations for this gene.

Product Details

Product: RAP1GAP FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: RAP1GAP-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping