RNF213 FISH Probe
The RNF213 FISH probe is designed to hybridize to the RNF213 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RNF213-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RNF213-20-RE | 20 (40 μL) | 200 μL |  |
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| RNF213-20-GO | 20 (40 μL) | 200 μL |  |
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| RNF213-20-GR | 20 (40 μL) | 200 μL |  |
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| RNF213-20-AQ | 20 (40 μL) | 200 μL |  |
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| RNF213-20-DIG | 20 (40 μL) | 200 μL |  |
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| RNF213-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2;17)(p23;q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8;17)(q24;q25) translocation has been identified with the MYC gene on chromosome 8. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2011]
Gene Details
Gene Symbol: RNF213
Gene Name: Ring Finger Protein 213
Chromosome: CHR17: 78234666-78370086
Locus: 17q25.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: RNF213 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RNF213-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping