S100B FISH Probe
The S100B FISH probe is designed to hybridize to the S100B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| S100B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| S100B-20-RE | 20 (40 μL) | 200 μL |  |
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| S100B-20-GO | 20 (40 μL) | 200 μL |  |
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| S100B-20-GR | 20 (40 μL) | 200 μL |  |
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| S100B-20-AQ | 20 (40 μL) | 200 μL |  |
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| S100B-20-DIG | 20 (40 μL) | 200 μL |  |
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| S100B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: S100B
Gene Name: S100 Calcium Binding Protein B
Chromosome: CHR21: 48018530-48025035
Locus: 21q22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: S100B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: S100B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping