SELENOS FISH Probe
The SELENOS FISH probe is designed to hybridize to the SELENOS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SELENOS-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SELENOS-20-RE | 20 (40 μL) | 200 μL |  |
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| SELENOS-20-GO | 20 (40 μL) | 200 μL |  |
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| SELENOS-20-GR | 20 (40 μL) | 200 μL |  |
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| SELENOS-20-AQ | 20 (40 μL) | 200 μL |  |
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| SELENOS-20-DIG | 20 (40 μL) | 200 μL |  |
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| SELENOS-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a transmembrane protein that is localized in the endoplasmic reticulum (ER). It is involved in the degradation process of misfolded proteins in the ER, and may also have a role in inflammation control. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Two additional phylogenetically conserved stem-loop structures (Stem-loop 1 and Stem-loop 2) in the 3' UTR of this mRNA have been shown to function as modulators of Sec insertion. An alternatively spliced transcript variant, lacking the SECIS element and encoding a non-Sec containing shorter isoform, has been described for this gene (PMID:23614019). [provided by RefSeq, Jul 2017]
Gene Details
Gene Symbol: SELENOS
Gene Name: Selenoprotein S
Chromosome: CHR15: 101277519-101270908
Locus: 15q26.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: SELENOS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SELENOS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping