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SPHK1 FISH Probe

The SPHK1 FISH probe is designed to hybridize to the SPHK1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SPHK1-20-OR  (Standard Design) 20 (40 μL) 200 μL
SPHK1-20-RE 20 (40 μL) 200 μL
SPHK1-20-GO 20 (40 μL) 200 μL
SPHK1-20-GR 20 (40 μL) 200 μL
SPHK1-20-AQ 20 (40 μL) 200 μL
SPHK1-20-DIG 20 (40 μL) 200 μL
SPHK1-20-BIO 20 (40 μL) 200 μL

Gene Summary

The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Phosphorylation of this protein alters its catalytic activity and promotes its translocation to the plasma membrane. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2017]

Gene Details

Gene Symbol: SPHK1

Gene Name: Sphingosine Kinase 1

Chromosome: CHR17: 74380689-74383941

Locus: 17q25.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: SPHK1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SPHK1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping