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STIN2-VNTR FISH Probe

The STIN2-VNTR FISH probe is designed to hybridize to the STIN2-VNTR gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
STIN2-VNTR-20-OR  (Standard Design) 20 (40 μL) 200 μL
STIN2-VNTR-20-RE 20 (40 μL) 200 μL
STIN2-VNTR-20-GO 20 (40 μL) 200 μL
STIN2-VNTR-20-GR 20 (40 μL) 200 μL
STIN2-VNTR-20-AQ 20 (40 μL) 200 μL
STIN2-VNTR-20-DIG 20 (40 μL) 200 μL
STIN2-VNTR-20-BIO 20 (40 μL) 200 μL

Gene Summary

This genomic sequence represents the STin2 enhancer element in an intron of the solute carrier family 6 member 4 (SLC6A4) gene on chromosome 17. It also represents a polymorphic region consisting of a variable number of tandem repeats (VNTR), where each repeat unit is 16-17 bp in length. Three major alleles have been identified in human populations, STin2.9, STin2.10 and STin2.12, carrying 9, 10 and 12 copies of the repeat unit, respectively. Enhancer activity levels vary based on the allele, with each repeat unit making varying contributions to activity. This region can bind to transcription factors including CTCF and YB-1, and it may also co-operate with the 5-HTTLPR regulatory element, which is another VNTR polymorphic region located in the SLC6A4 promoter. Polymorphisms in this STin2 region may be associated with a variety of mood, behavioral and stress-related psychopathologies, possibly in a population-dependent fashion, in combination with other polymorphisms (such as the 5-HTTLPR), and/or related to epigenetic processes. [provided by RefSeq, Aug 2017]

Gene Details

Gene Symbol: STIN2-VNTR

Gene Name: Serotonin Transporter Intronic VNTR Enhancer

Locus: 17q11.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: STIN2-VNTR FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: STIN2-VNTR-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping