TAGLN FISH Probe
The TAGLN FISH probe is designed to hybridize to the TAGLN gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TAGLN-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TAGLN-20-RE | 20 (40 μL) | 200 μL |  |
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| TAGLN-20-GO | 20 (40 μL) | 200 μL |  |
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| TAGLN-20-GR | 20 (40 μL) | 200 μL |  |
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| TAGLN-20-AQ | 20 (40 μL) | 200 μL |  |
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| TAGLN-20-DIG | 20 (40 μL) | 200 μL |  |
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| TAGLN-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a shape change and transformation sensitive actin-binding protein which belongs to the calponin family. It is ubiquitously expressed in vascular and visceral smooth muscle, and is an early marker of smooth muscle differentiation. The encoded protein is thought to be involved in calcium-independent smooth muscle contraction. It acts as a tumor suppressor, and the loss of its expression is an early event in cell transformation and the development of some tumors, coinciding with cellular plasticity. The encoded protein has a domain architecture consisting of an N-terminal calponin homology (CH) domain and a C-terminal calponin-like (CLIK) domain. Mice with a knockout of the orthologous gene are viable and fertile but their vascular smooth muscle cells exhibit alterations in the distribution of the actin filament and changes in cytoskeletal organization. [provided by RefSeq, Aug 2017]
Gene Details
Gene Symbol: TAGLN
Gene Name: Transgelin
Chromosome: CHR11: 117070039-117075508
Locus: 11q23.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TAGLN FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TAGLN-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping