TOP3A FISH Probe
The TOP3A FISH probe is designed to hybridize to the TOP3A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| TOP3A-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| TOP3A-20-RE | 20 (40 μL) | 200 μL |  |
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| TOP3A-20-GO | 20 (40 μL) | 200 μL |  |
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| TOP3A-20-GR | 20 (40 μL) | 200 μL |  |
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| TOP3A-20-AQ | 20 (40 μL) | 200 μL |  |
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| TOP3A-20-DIG | 20 (40 μL) | 200 μL |  |
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| TOP3A-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus reducing the number of supercoils and altering the topology of DNA. This enzyme forms a complex with BLM which functions in the regulation of recombination in somatic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2016]
Gene Details
Gene Symbol: TOP3A
Gene Name: DNA Topoisomerase III Alpha
Chromosome: CHR17: 18177234-18218321
Locus: 17p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: TOP3A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: TOP3A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping