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TPMT FISH Probe

The TPMT FISH probe is designed to hybridize to the TPMT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
TPMT-20-OR  (Standard Design) 20 (40 μL) 200 μL
TPMT-20-RE 20 (40 μL) 200 μL
TPMT-20-GO 20 (40 μL) 200 μL
TPMT-20-GR 20 (40 μL) 200 μL
TPMT-20-AQ 20 (40 μL) 200 μL
TPMT-20-DIG 20 (40 μL) 200 μL
TPMT-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. [provided by RefSeq, Aug 2014]

Gene Details

Gene Symbol: TPMT

Gene Name: Thiopurine S-methyltransferase

Chromosome: CHR6: 18128544-18155374

Locus: 6p22.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: TPMT FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: TPMT-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping