UMPS FISH Probe
The UMPS FISH probe is designed to hybridize to the UMPS gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UMPS-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| UMPS-20-RE | 20 (40 μL) | 200 μL |  |
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| UMPS-20-GO | 20 (40 μL) | 200 μL |  |
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| UMPS-20-GR | 20 (40 μL) | 200 μL |  |
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| UMPS-20-AQ | 20 (40 μL) | 200 μL |  |
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| UMPS-20-DIG | 20 (40 μL) | 200 μL |  |
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| UMPS-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a uridine 5'-monophosphate synthase. The encoded protein is a bifunctional enzyme that catalyzes the final two steps of the de novo pyrimidine biosynthetic pathway. The first reaction is carried out by the N-terminal enzyme orotate phosphoribosyltransferase which converts orotic acid to orotidine-5'-monophosphate. The terminal reaction is carried out by the C-terminal enzyme OMP decarboxylase which converts orotidine-5'-monophosphate to uridine monophosphate. Defects in this gene are the cause of hereditary orotic aciduria. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
Gene Details
Gene Symbol: UMPS
Gene Name: Uridine Monophosphate Synthetase
Chromosome: CHR3: 124449212-124468119
Locus: 3q21.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: UMPS FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UMPS-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping