UPF1 FISH Probe
The UPF1 FISH probe is designed to hybridize to the UPF1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| UPF1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| UPF1-20-RE | 20 (40 μL) | 200 μL |  |
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| UPF1-20-GO | 20 (40 μL) | 200 μL |  |
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| UPF1-20-GR | 20 (40 μL) | 200 μL |  |
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| UPF1-20-AQ | 20 (40 μL) | 200 μL |  |
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| UPF1-20-DIG | 20 (40 μL) | 200 μL |  |
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| UPF1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Details
Gene Symbol: UPF1
Gene Name: UPF1, RNA Helicase And ATPase
Chromosome: CHR19: 18942743-18979039
Locus: 19p13.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: UPF1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: UPF1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping