USP20 FISH Probe
The USP20 FISH probe is designed to hybridize to the USP20 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| USP20-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| USP20-20-RE | 20 (40 μL) | 200 μL |  |
|
| USP20-20-GO | 20 (40 μL) | 200 μL |  |
|
| USP20-20-GR | 20 (40 μL) | 200 μL |  |
|
| USP20-20-AQ | 20 (40 μL) | 200 μL |  |
|
| USP20-20-DIG | 20 (40 μL) | 200 μL |  |
|
| USP20-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex. In addition to being ubiquitinated by the VHL-E3 ligase complex, this enzyme deubiquitinates hypoxia-inducible factor (HIF)-1 alpha and thereby causes increased expression of HIF-1alpha targeted genes which play a role in angiogenesis, glucose metabolism, cell proliferation and metastasis. The enzyme encoded by this gene also regulates G-protein coupled receptor signaling by mediating the deubiquitination of beta-2 adrenergic receptor (ADRB2). This enzyme is a ubiquitously expressed thiolester hydrolase. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jan 2013]
Gene Details
Gene Symbol: USP20
Gene Name: Ubiquitin Specific Peptidase 20
Chromosome: CHR9: 132597695-132644107
Locus: 9q34.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: USP20 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: USP20-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping