VRK1 FISH Probe
The VRK1 FISH probe is designed to hybridize to the VRK1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| VRK1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| VRK1-20-RE | 20 (40 μL) | 200 μL |  |
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| VRK1-20-GO | 20 (40 μL) | 200 μL |  |
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| VRK1-20-GR | 20 (40 μL) | 200 μL |  |
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| VRK1-20-AQ | 20 (40 μL) | 200 μL |  |
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| VRK1-20-DIG | 20 (40 μL) | 200 μL |  |
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| VRK1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: VRK1
Gene Name: Vaccinia Related Kinase 1
Chromosome: CHR14: 97263683-97347951
Locus: 14q32.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: VRK1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: VRK1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping