ZP4 FISH Probe
The ZP4 FISH probe is designed to hybridize to the ZP4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ZP4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| ZP4-20-RE | 20 (40 μL) | 200 μL |  |
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| ZP4-20-GO | 20 (40 μL) | 200 μL |  |
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| ZP4-20-GR | 20 (40 μL) | 200 μL |  |
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| ZP4-20-AQ | 20 (40 μL) | 200 μL |  |
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| ZP4-20-DIG | 20 (40 μL) | 200 μL |  |
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| ZP4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: ZP4
Gene Name: Zona Pellucida Glycoprotein 4
Chromosome: CHR1: 238041163-238054222
Locus: 1q43
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: ZP4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: ZP4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping