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ABL2 Break Apart FISH Probe

Our ABL2 break apart probe is designed to detect ABL2 translocations. The probe comes labeled in orange and green, but can be customized to meet your needs. 

Gene Background: ABL2 belongs to the same gene family of Abelson nonreceptor tyrosine kinases as ABL1. It regulates actin rearrangement via phosphorylation of cytoskeleton-remodeling proteins, including MYH10, CTTN, and TUBB. ABL2 rearrangements have been identified in several leukemias, often resulting in fusions with ETV6.

Source: GeneCards.org

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ABL2BA-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ABL2BA-20-GRGO 20 (40 μL) 200 μL
ABL2BA-20-GOGR 20 (40 μL) 200 μL
ABL2BA-20-GROR 20 (40 μL) 200 μL
ABL2BA-20-REGR 20 (40 μL) 200 μL
ABL2BA-20-GRRE 20 (40 μL) 200 μL

Gene Summary

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]

Gene Details

Gene Symbol: ABL2

Gene Name: ABL Proto-oncogene 2, Non-receptor Tyrosine Kinase

Chromosome: CHR1: 179068461-179198819

Locus: 1q25.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.