SKP2 FISH Probe
Empire Genomics has developed an SKP2 FISH probe to detect SKP2 gene aneusomy. The SKP2 FISH probe comes labeled in orange, and you may also choose to customize the probe to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SKP2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |
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| SKP2-20-GO | 20 (40 μL) | 200 μL |
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| SKP2-20-GR | 20 (40 μL) | 200 μL |
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| SKP2-20-AQ | 20 (40 μL) | 200 μL |
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| SKP2-20-RE | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class; in addition to an F-box, this protein contains 10 tandem leucine-rich repeats. This protein is an essential element of the cyclin A-CDK2 S-phase kinase. It specifically recognizes phosphorylated cyclin-dependent kinase inhibitor 1B (CDKN1B, also referred to as p27 or KIP1) predominantly in S phase and interacts with S-phase kinase-associated protein 1 (SKP1 or p19). In addition, this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas. Alternative splicing of this gene generates three transcript variants encoding different isoforms. [provided by RefSeq, Jul 2011]
Gene Details
Gene Symbol: SKP2
Gene Name: S-phase Kinase Associated Protein 2
Chromosome: CHR5: 36152144-36184142
Locus: 5p13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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