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NRAS FISH Probe

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

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NRAS-10-RE  (Standard Design) 10 (20 μL) 100 μL

Gene Summary

This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia. [provided by RefSeq, Jun 2011]

Gene Details

Gene Symbol: NRAS

Gene Name: NRAS Proto-oncogene, GTPase

Chromosome: CHR1: 115247084-115259515

Locus: 1p13.2

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.