FAM135A-FBXL4 Fusion FISH Probe
The FAM135A-FBXL4 Fusion FISH Probe is used to confirm a fusion of the FAM135A and FBXL4 genes. The fusion of the FAM135A and FBXL4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM135A-FBXL4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-RERE | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-REOR | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-REGO | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-REGR | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-OROR | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-GORE | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-GROR | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM135A-FBXL4-20-AQAQ | 20 (40 μL) | 200 μL |
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FBXL4 Gene Summary
This gene encodes a member of the F-box protein family, which are characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one subunit of modular E3 ubiquitin ligase complexes, called SCF complexes, which function in phosphorylation-dependent ubiquitination. The F-box domain mediates protein-protein interactions and binds directly to S-phase kinase-associated protein 1. In addition to an F-box domain, the encoded protein contains at least 9 tandem leucine-rich repeats. The ubiquitin ligase complex containing the encoded protein may function in cell-cycle control by regulating levels of lysine-specific demethylase 4A. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Gene Name: F-box And Leucine Rich Repeat Protein 4
Chromosome: CHR6: 99321600 -99395849
Locus: 6q16.1-q16.2
FAM135A Gene Summary
The Family With Sequence Similarity 135 Member A (FAM135A) gene is located on chr6 :71123106-71270877 at 6q13.
Gene Name: Family With Sequence Similarity 135 Member A
Chromosome: CHR6: 71123106 -71270877
Locus: 6q13
Gene Diseases
The FAM135A FBXL4 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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