FAM160A1-IL15 Fusion FISH Probe
The FAM160A1-IL15 Fusion FISH Probe is used to confirm a fusion of the FAM160A1 and IL15 genes. The fusion of the FAM160A1 and IL15 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM160A1-IL15-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-RERE | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-REOR | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-REGO | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-REGR | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-OROR | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-GORE | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-GROR | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM160A1-IL15-20-AQAQ | 20 (40 μL) | 200 μL |
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IL15 Gene Summary
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number of CD8+ memory cells is shown to be controlled by a balance between this cytokine and IL2. This cytokine induces the activation of JAK kinases, as well as the phosphorylation and activation of transcription activators STAT3, STAT5, and STAT6. Studies of the mouse counterpart suggested that this cytokine may increase the expression of apoptosis inhibitor BCL2L1/BCL-x(L), possibly through the transcription activation activity of STAT6, and thus prevent apoptosis. Alternatively spliced transcript variants of this gene have been reported. [provided by RefSeq, Feb 2011]
Gene Name: Interleukin 15
Chromosome: CHR4: 142557748 -142655140
Locus: 4q31.21
FAM160A1 Gene Summary
The Family With Sequence Similarity 160 Member A1 (FAM160A1) gene is located on chr4 :152330397-152584784 at 4q31.3.
Gene Name: Family With Sequence Similarity 160 Member A1
Chromosome: CHR4: 152330397 -152584784
Locus: 4q31.3
Gene Diseases
The FAM160A1 IL15 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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