FAM160A2-APBB1 Fusion FISH Probe
The FAM160A2-APBB1 Fusion FISH Probe is used to confirm a fusion of the FAM160A2 and APBB1 genes. The fusion of the FAM160A2 and APBB1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| FAM160A2-APBB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-RERE | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-REOR | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-REGO | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-REGR | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-REAQ | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-ORRE | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-OROR | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-ORGO | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-GORE | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-GOOR | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-GOGO | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-GOGR | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-GRRE | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-GROR | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-GRGO | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-GRGR | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-AQRE | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-AQOR | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-AQGO | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-AQGR | 20 (40 μL) | 200 μL |
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| FAM160A2-APBB1-20-AQAQ | 20 (40 μL) | 200 μL |
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APBB1 Gene Summary
The protein encoded by this gene is a member of the Fe65 protein family. It is an adaptor protein localized in the nucleus. It interacts with the Alzheimer's disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1 and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. This encoded protein could play an important role in the pathogenesis of Alzheimer's disease. It is thought to regulate transcription. Also it is observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2012]
Gene Name: Amyloid Beta Precursor Protein Binding Family B Member 1
Chromosome: CHR11: 6416354 -6440644
Locus: 11p15.4
FAM160A2 Gene Summary
The protein encoded by this gene is part of the FTS/Hook/FHIP (FHF) complex, which can interact with members of the homotypic vesicular protein sorting (HOPS) complex. This interaction suggests that the encoded protein is involved in vesicle trafficking. [provided by RefSeq, Dec 2016]
Gene Name: Family With Sequence Similarity 160 Member A2
Chromosome: CHR11: 6232563 -6255941
Locus: 11p15.4
Gene Diseases
The FAM160A2 APBB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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