LTBP1-CDH23 Fusion FISH Probe
The LTBP1-CDH23 Fusion FISH Probe is used to confirm a fusion of the LTBP1 and CDH23 genes. The fusion of the LTBP1 and CDH23 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| LTBP1-CDH23-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-RERE | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-REOR | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-REGO | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-REGR | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-REAQ | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-ORRE | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-OROR | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-ORGO | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-ORAQ | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-GORE | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-GOOR | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-GOGO | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-GOGR | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-GOAQ | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-GRRE | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-GROR | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-GRGO | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-GRGR | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-GRAQ | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-AQRE | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-AQOR | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-AQGO | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-AQGR | 20 (40 μL) | 200 μL |
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| LTBP1-CDH23-20-AQAQ | 20 (40 μL) | 200 μL |
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LTBP1 Gene Summary
The protein encoded by this gene belongs to the family of latent TGF-beta binding proteins (LTBPs). The secretion and activation of TGF-betas is regulated by their association with latency-associated proteins and with latent TGF-beta binding proteins. The product of this gene targets latent complexes of transforming growth factor beta to the extracellular matrix, where the latent cytokine is subsequently activated by several different mechanisms. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Latent Transforming Growth Factor Beta Binding Protein 1
Chromosome: CHR2: 33172368 -33624575
Locus: 2p22.3
CDH23 Gene Summary
This gene is a member of the cadherin superfamily, whose genes encode calcium dependent cell-cell adhesion glycoproteins. The encoded protein is thought to be involved in stereocilia organization and hair bundle formation. The gene is located in a region containing the human deafness loci DFNB12 and USH1D. Usher syndrome 1D and nonsyndromic autosomal recessive deafness DFNB12 are caused by allelic mutations of this cadherin-like gene. Upregulation of this gene may also be associated with breast cancer. Alternative splice variants encoding different isoforms have been described. [provided by RefSeq, May 2013]
Gene Name: Cadherin Related 23
Chromosome: CHR10: 73156690 -73575704
Locus: 10q22.1
Gene Diseases
The LTBP1 CDH23 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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