NUP43-SHPRH Fusion FISH Probe
The NUP43-SHPRH Fusion FISH Probe is used to confirm a fusion of the NUP43 and SHPRH genes. The fusion of the NUP43 and SHPRH genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| NUP43-SHPRH-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-RERE | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-REOR | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-REGO | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-REGR | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-REAQ | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-ORRE | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-OROR | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-ORGO | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-ORAQ | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-GORE | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-GOOR | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-GOGO | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-GOGR | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-GOAQ | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-GRRE | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-GROR | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-GRGO | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-GRGR | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-GRAQ | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-AQRE | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-AQOR | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-AQGO | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-AQGR | 20 (40 μL) | 200 μL |
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| NUP43-SHPRH-20-AQAQ | 20 (40 μL) | 200 μL |
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SHPRH Gene Summary
SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
Gene Name: SNF2 Histone Linker PHD RING Helicase
Chromosome: CHR6: 146205944 -146285233
Locus: 6q24.3
NUP43 Gene Summary
Bidirectional transport of macromolecules between the cytoplasm and nucleus occurs through nuclear pore complexes (NPCs) embedded in the nuclear envelope. NPCs are composed of subcomplexes, and NUP43 is part of one such subcomplex, Nup107-160 (Loiodice et al., 2004 [PubMed 15146057]).[supplied by OMIM, Mar 2008]
Gene Name: Nucleoporin 43
Chromosome: CHR6: 150045456 -150067688
Locus: 6q25.1
Gene Diseases
The NUP43 SHPRH Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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