ODZ3-NR3C2 Fusion FISH Probe
The ODZ3-NR3C2 Fusion FISH Probe is used to confirm a fusion of the ODZ3 and NR3C2 genes. The fusion of the ODZ3 and NR3C2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ODZ3-NR3C2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-RERE | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-REOR | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-REGO | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-REGR | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-REAQ | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-ORRE | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-OROR | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-ORGO | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-ORAQ | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-GORE | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-GOOR | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-GOGO | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-GOGR | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-GOAQ | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-GRRE | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-GROR | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-GRGO | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-GRGR | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-GRAQ | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-AQRE | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-AQOR | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-AQGO | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-AQGR | 20 (40 μL) | 200 μL |
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| ODZ3-NR3C2-20-AQAQ | 20 (40 μL) | 200 μL |
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NR3C2 Gene Summary
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Gene Name: Nuclear Receptor Subfamily 3 Group C Member 2
Chromosome: CHR4: 148999914 -149363672
Locus: 4q31.23
Gene Diseases
The ODZ3 NR3C2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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