TP53BP2-WDR26 Fusion FISH Probe
The TP53BP2-WDR26 Fusion FISH Probe is used to confirm a fusion of the TP53BP2 and WDR26 genes. The fusion of the TP53BP2 and WDR26 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| TP53BP2-WDR26-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-RERE | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-REOR | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-REGO | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-REGR | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-REAQ | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-ORRE | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-OROR | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-ORGO | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-ORAQ | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-GORE | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-GOOR | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-GOGO | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-GOGR | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-GOAQ | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-GRRE | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-GROR | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-GRGO | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-GRGR | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-GRAQ | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-AQRE | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-AQOR | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-AQGO | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-AQGR | 20 (40 μL) | 200 μL |
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| TP53BP2-WDR26-20-AQAQ | 20 (40 μL) | 200 μL |
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TP53BP2 Gene Summary
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Tumor Protein P53 Binding Protein 2
Chromosome: CHR1: 223967594 -224033674
Locus: 1q41
WDR26 Gene Summary
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: WD Repeat Domain 26
Chromosome: CHR1: 224572844 -224622001
Locus: 1q42.11-q42.12
Gene Diseases
The TP53BP2 WDR26 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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