ZFAND2B-CYP27A1 Fusion FISH Probe
The ZFAND2B-CYP27A1 Fusion FISH Probe is used to confirm a fusion of the ZFAND2B and CYP27A1 genes. The fusion of the ZFAND2B and CYP27A1 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ZFAND2B-CYP27A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-RERE | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-REOR | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-REGO | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-REGR | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-REAQ | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-ORRE | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-OROR | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-ORGO | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-GORE | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-GOOR | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-GOGO | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-GOGR | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-GRRE | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-GROR | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-GRGO | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-GRGR | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-AQRE | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-AQOR | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-AQGO | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-AQGR | 20 (40 μL) | 200 μL |
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| ZFAND2B-CYP27A1-20-AQAQ | 20 (40 μL) | 200 μL |
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CYP27A1 Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Family 27 Subfamily A Member 1
Chromosome: CHR2: 219646471 -219680016
Locus: 2q35
ZFAND2B Gene Summary
This gene encodes a protein containing AN1-type zinc-fingers and ubiquitin-interacting motifs. The encoded protein likely associates with the proteosome to stimulate the degradation of toxic or misfolded proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]
Gene Name: Zinc Finger AN1-type Containing 2B
Chromosome: CHR2: 220071537 -220074370
Locus: 2q35
Gene Diseases
The ZFAND2B CYP27A1 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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