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Engineering of systematic elimination of a targeted chromosome in human cells

Embryonic trisomy leads to abortion or congenital genetic disorders in humans. The most common autosomal chromosome abnormalities are trisomy of chro...

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Expression and trafficking of placental microRNAs at the feto-maternal interface

During pregnancy, placental trophoblasts at the feto-maternal interface produce a broad repertoire of microRNA (miRNA) species. These species include ...

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CANT1 lncRNA triggers efficient therapeutic efficacy by correcting aberrant lncing cascade in malignant uveal melanoma

Uveal melanoma (UM) is an intraocular malignant tumor with high mortality rate.Recent studies have shown the functions of long non-coding RNAs (lncRNA...

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