ACTA2-COL6A1 Fusion FISH Probe
The ACTA2-COL6A1 Fusion FISH Probe is used to confirm a fusion of the ACTA2 and COL6A1 genes. The fusion of the ACTA2 and COL6A1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACTA2-COL6A1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ACTA2-COL6A1-20-AQAQ | 20 (40 μL) | 200 μL |
|
ACTA2 Gene Summary
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a smooth muscle actin that is involved in vascular contractility and blood pressure homeostasis. Mutations in this gene cause a variety of vascular diseases, such as thoracic aortic disease, coronary artery disease, stroke, and Moyamoya disease, as well as multisystemic smooth muscle dysfunction syndrome. [provided by RefSeq, Sep 2017]
Gene Name: Actin, Alpha 2, Smooth Muscle, Aorta
Chromosome: CHR10: 90694830 -90751147
Locus: 10q23.31
COL6A1 Gene Summary
The collagens are a superfamily of proteins that play a role in maintaining the integrity of various tissues. Collagens are extracellular matrix proteins and have a triple-helical domain as their common structural element. Collagen VI is a major structural component of microfibrils. The basic structural unit of collagen VI is a heterotrimer of the alpha1(VI), alpha2(VI), and alpha3(VI) chains. The alpha2(VI) and alpha3(VI) chains are encoded by the COL6A2 and COL6A3 genes, respectively. The protein encoded by this gene is the alpha 1 subunit of type VI collagen (alpha1(VI) chain). Mutations in the genes that code for the collagen VI subunits result in the autosomal dominant disorder, Bethlem myopathy. [provided by RefSeq, Jul 2008]
Gene Name: Collagen Type VI Alpha 1 Chain
Chromosome: CHR21: 47401662 -47424963
Locus: 21q22.3
Gene Diseases
The ACTA2 COL6A1 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|