ACTB-CSE1L Fusion FISH Probe
The ACTB-CSE1L Fusion FISH Probe is used to confirm a fusion of the ACTB and CSE1L genes. The fusion of the ACTB and CSE1L genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ACTB-CSE1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-RERE | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-REOR | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-REGO | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-REGR | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-REAQ | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-ORRE | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-OROR | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-ORGO | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-GORE | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-GOOR | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-GOGO | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-GOGR | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-GRRE | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-GROR | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-GRGO | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-GRGR | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-AQRE | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-AQOR | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-AQGO | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-AQGR | 20 (40 μL) | 200 μL |
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| ACTB-CSE1L-20-AQAQ | 20 (40 μL) | 200 μL |
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ACTB Gene Summary
This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017]
Gene Name: Actin Beta
Chromosome: CHR7: 5566778 -5570232
Locus: 7p22.1
CSE1L Gene Summary
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Name: Chromosome Segregation 1 Like
Chromosome: CHR20: 47662837 -47713486
Locus: 20q13.13
Gene Diseases
The ACTB CSE1L Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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