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ACTB-PMP2 Fusion FISH Probe

The ACTB-PMP2 Fusion FISH Probe is used to confirm a fusion of the ACTB and PMP2 genes. The fusion of the ACTB and PMP2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ACTB-PMP2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ACTB-PMP2-20-RERE 20 (40 μL) 200 μL
ACTB-PMP2-20-REOR 20 (40 μL) 200 μL
ACTB-PMP2-20-REGO 20 (40 μL) 200 μL
ACTB-PMP2-20-REGR 20 (40 μL) 200 μL
ACTB-PMP2-20-REAQ 20 (40 μL) 200 μL
ACTB-PMP2-20-ORRE 20 (40 μL) 200 μL
ACTB-PMP2-20-OROR 20 (40 μL) 200 μL
ACTB-PMP2-20-ORGO 20 (40 μL) 200 μL
ACTB-PMP2-20-ORAQ 20 (40 μL) 200 μL
ACTB-PMP2-20-GORE 20 (40 μL) 200 μL
ACTB-PMP2-20-GOOR 20 (40 μL) 200 μL
ACTB-PMP2-20-GOGO 20 (40 μL) 200 μL
ACTB-PMP2-20-GOGR 20 (40 μL) 200 μL
ACTB-PMP2-20-GOAQ 20 (40 μL) 200 μL
ACTB-PMP2-20-GRRE 20 (40 μL) 200 μL
ACTB-PMP2-20-GROR 20 (40 μL) 200 μL
ACTB-PMP2-20-GRGO 20 (40 μL) 200 μL
ACTB-PMP2-20-GRGR 20 (40 μL) 200 μL
ACTB-PMP2-20-GRAQ 20 (40 μL) 200 μL
ACTB-PMP2-20-AQRE 20 (40 μL) 200 μL
ACTB-PMP2-20-AQOR 20 (40 μL) 200 μL
ACTB-PMP2-20-AQGO 20 (40 μL) 200 μL
ACTB-PMP2-20-AQGR 20 (40 μL) 200 μL
ACTB-PMP2-20-AQAQ 20 (40 μL) 200 μL

ACTB Gene Summary

This gene encodes one of six different actin proteins. Actins are highly conserved proteins that are involved in cell motility, structure, integrity, and intercellular signaling. The encoded protein is a major constituent of the contractile apparatus and one of the two nonmuscle cytoskeletal actins that are ubiquitously expressed. Mutations in this gene cause Baraitser-Winter syndrome 1, which is characterized by intellectual disability with a distinctive facial appearance in human patients. Numerous pseudogenes of this gene have been identified throughout the human genome. [provided by RefSeq, Aug 2017]

Gene Name: Actin Beta

Chromosome: CHR7: 5566778 -5570232

Locus: 7p22.1

PMP2 Gene Summary

The protein encoded by this gene localizes to myelin sheaths of the peripheral nervous system. The encoded protein can bind both the membrane layers of the sheaths and monomeric lipids, and is thought to provide stability to the sheath. A defect in this gene was shown to be a cause of dominant demyelinating CMT neuropathy. [provided by RefSeq, Jan 2017]

Gene Name: Peripheral Myelin Protein 2

Chromosome: CHR8: 82352563 -82359719

Locus: 8q21.13

Gene Diseases

The ACTB PMP2 Fusion has been associated with the following diseases:

Disease Name
Brain Lower Grade Glioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.