ACTG1-CCT5 Fusion FISH Probe
The ACTG1-CCT5 Fusion FISH Probe is used to confirm a fusion of the ACTG1 and CCT5 genes. The fusion of the ACTG1 and CCT5 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| ACTG1-CCT5-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-RERE | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-REOR | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-REGO | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-REGR | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-OROR | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-GORE | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-GROR | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| ACTG1-CCT5-20-AQAQ | 20 (40 μL) | 200 μL |
|
ACTG1 Gene Summary
Actins are highly conserved proteins that are involved in various types of cell motility and in maintenance of the cytoskeleton. Three main groups of actin isoforms have been identified in vertebrate animals: alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the cytoskeleton and as mediators of internal cell motility. Actin gamma 1, encoded by this gene, is a cytoplasmic actin found in all cell types. Mutations in this gene are associated with DFNA20/26, a subtype of autosomal dominant non-syndromic sensorineural progressive hearing loss and also with Baraitser-Winter syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2017]
Gene Name: Actin Gamma 1
Chromosome: CHR17: 79476996 -79479892
Locus: 17q25.3
CCT5 Gene Summary
The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]
Gene Name: Chaperonin Containing TCP1 Subunit 5
Chromosome: CHR5: 10250281 -10266501
Locus: 5p15.2
Gene Diseases
The ACTG1 CCT5 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|