ADAMTS16-ETV6 Fusion FISH Probe
The ADAMTS16-ETV6 Fusion FISH Probe is used to confirm a fusion of the ADAMTS16 and ETV6 genes. The fusion of the ADAMTS16 and ETV6 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADAMTS16-ETV6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-RERE | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-REOR | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-REGO | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-REGR | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-REAQ | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-ORRE | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-OROR | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-ORGO | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-GORE | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-GOOR | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-GOGO | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-GOGR | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-GRRE | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-GROR | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-GRGO | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-GRGR | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-AQRE | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-AQOR | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-AQGO | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-AQGR | 20 (40 μL) | 200 μL |
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| ADAMTS16-ETV6-20-AQAQ | 20 (40 μL) | 200 μL |
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ETV6 Gene Summary
This gene encodes an ETS family transcription factor. The product of this gene contains two functional domains: a N-terminal pointed (PNT) domain that is involved in protein-protein interactions with itself and other proteins, and a C-terminal DNA-binding domain. Gene knockout studies in mice suggest that it is required for hematopoiesis and maintenance of the developing vascular network. This gene is known to be involved in a large number of chromosomal rearrangements associated with leukemia and congenital fibrosarcoma. [provided by RefSeq, Sep 2008]
Gene Name: ETS Variant 6
Chromosome: CHR12: 11802787 -12048325
Locus: 12p13.2
ADAMTS16 Gene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. ADAMTS family members share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protein, which may inhibit chondrosarcoma cell proliferation and migration. This gene may regulate blood pressure. [provided by RefSeq, May 2016]
Gene Name: ADAM Metallopeptidase With Thrombospondin Type 1 Motif 16
Chromosome: CHR5: 5140442 -5320412
Locus: 5p15.32
Gene Diseases
The ADAMTS16 ETV6 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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