ADAMTS7-TMEM135 Fusion FISH Probe
The ADAMTS7-TMEM135 Fusion FISH Probe is used to confirm a fusion of the ADAMTS7 and TMEM135 genes. The fusion of the ADAMTS7 and TMEM135 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADAMTS7-TMEM135-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-RERE | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-REOR | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-REGO | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-REGR | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-REAQ | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-ORRE | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-OROR | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-ORGO | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-GORE | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-GOOR | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-GOGO | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-GOGR | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-GRRE | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-GROR | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-GRGO | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-GRGR | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-AQRE | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-AQOR | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-AQGO | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-AQGR | 20 (40 μL) | 200 μL |
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| ADAMTS7-TMEM135-20-AQAQ | 20 (40 μL) | 200 μL |
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ADAMTS7 Gene Summary
The protein encoded by this gene is a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family. Members of this family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and may regulate vascular smooth muscle cell (VSMC) migration. Mutations in this gene may be associated with susceptibility to coronary artery disease. [provided by RefSeq, Feb 2016]
Gene Name: ADAM Metallopeptidase With Thrombospondin Type 1 Motif 7
Chromosome: CHR15: 79051544 -79103773
Locus: 15q25.1
TMEM135 Gene Summary
The Transmembrane Protein 135 (TMEM135) gene is located on chr11 :86748885-87039876 at 11q14.2.
Gene Name: Transmembrane Protein 135
Chromosome: CHR11: 86748885 -87039876
Locus: 11q14.2
Gene Diseases
The ADAMTS7 TMEM135 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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