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ADAMTSL1-WNT5B Fusion FISH Probe

The ADAMTSL1-WNT5B Fusion FISH Probe is used to confirm a fusion of the ADAMTSL1 and WNT5B genes. The fusion of the ADAMTSL1 and WNT5B genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
ADAMTSL1-WNT5B-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-RERE 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-REOR 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-REGO 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-REGR 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-REAQ 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-ORRE 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-OROR 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-ORGO 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-ORAQ 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-GORE 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-GOOR 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-GOGO 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-GOGR 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-GOAQ 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-GRRE 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-GROR 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-GRGO 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-GRGR 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-GRAQ 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-AQRE 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-AQOR 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-AQGO 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-AQGR 20 (40 μL) 200 μL
ADAMTSL1-WNT5B-20-AQAQ 20 (40 μL) 200 μL

WNT5B Gene Summary

The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 94% and 80% amino acid identity to the mouse Wnt5b protein and the human WNT5A protein, respectively. Alternative splicing of this gene generates 2 transcript variants. [provided by RefSeq, Jul 2008]

Gene Name: Wnt Family Member 5B

Chromosome: CHR12: 1726221 -1756377

Locus: 12p13.33

ADAMTSL1 Gene Summary

This gene encodes a secreted protein and member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]

Gene Name: ADAMTS Like 1

Chromosome: CHR9: 18474078 -18910947

Locus: 9p22.2-p22.1

Gene Diseases

The ADAMTSL1 WNT5B Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.