ADAMTSL2-MAPKAP1 Fusion FISH Probe
The ADAMTSL2-MAPKAP1 Fusion FISH Probe is used to confirm a fusion of the ADAMTSL2 and MAPKAP1 genes. The fusion of the ADAMTSL2 and MAPKAP1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADAMTSL2-MAPKAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-RERE | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-REOR | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-REGO | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-REGR | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-OROR | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-GORE | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-GROR | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| ADAMTSL2-MAPKAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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ADAMTSL2 Gene Summary
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) and ADAMTS-like protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene lacks the protease domain, and is therefore of a member of the the ADAMTS-like protein subfamily. It is a secreted glycoprotein that binds the cell surface and extracellular matrix; it also interacts with latent transforming growth factor beta binding protein 1. Mutations in this gene have been associated with geleophysic dysplasia. [provided by RefSeq, Feb 2009]
Gene Name: ADAMTS Like 2
Chromosome: CHR9: 136397285 -136440641
Locus: 9q34.2
MAPKAP1 Gene Summary
This gene encodes a protein that is highly similar to the yeast SIN1 protein, a stress-activated protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been described. Alternate polyadenylation sites as well as alternate 3' UTRs have been identified for transcripts of this gene. [provided by RefSeq, Jul 2008]
Gene Name: Mitogen-activated Protein Kinase Associated Protein 1
Chromosome: CHR9: 128199672 -128469513
Locus: 9q33.3
Gene Diseases
The ADAMTSL2 MAPKAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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