ADCY9-TFAP4 Fusion FISH Probe
The ADCY9-TFAP4 Fusion FISH Probe is used to confirm a fusion of the ADCY9 and TFAP4 genes. The fusion of the ADCY9 and TFAP4 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADCY9-TFAP4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-RERE | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-REOR | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-REGO | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-REGR | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-REAQ | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-ORRE | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-OROR | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-ORGO | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-GORE | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-GOOR | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-GOGO | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-GOGR | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-GRRE | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-GROR | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-GRGO | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-GRGR | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-AQRE | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-AQOR | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-AQGO | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-AQGR | 20 (40 μL) | 200 μL |
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| ADCY9-TFAP4-20-AQAQ | 20 (40 μL) | 200 μL |
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ADCY9 Gene Summary
Adenylate cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. It is regulated by a family of G protein-coupled receptors, protein kinases, and calcium. The type 9 adenylyl cyclase is a widely distributed adenylyl cyclase, and it is stimulated by beta-adrenergic receptor activation but is insensitive to forskolin, calcium, and somatostatin. [provided by RefSeq, Jul 2008]
Gene Name: Adenylate Cyclase 9
Chromosome: CHR16: 4012649 -4166186
Locus: 16p13.3
TFAP4 Gene Summary
Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).[supplied by OMIM, Jul 2009]
Gene Name: Transcription Factor AP-4
Chromosome: CHR16: 4307186 -4323001
Locus: 16p13.3
Gene Diseases
The ADCY9 TFAP4 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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