ADIPOR2-ERC1 Fusion FISH Probe
The ADIPOR2-ERC1 Fusion FISH Probe is used to confirm a fusion of the ADIPOR2 and ERC1 genes. The fusion of the ADIPOR2 and ERC1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADIPOR2-ERC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-RERE | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-REOR | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-REGO | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-REGR | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-REAQ | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-ORRE | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-OROR | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-ORGO | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-GORE | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-GOOR | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-GOGO | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-GOGR | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-GRRE | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-GROR | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-GRGO | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-GRGR | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-AQRE | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-AQOR | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-AQGO | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-AQGR | 20 (40 μL) | 200 μL |
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| ADIPOR2-ERC1-20-AQAQ | 20 (40 μL) | 200 μL |
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ERC1 Gene Summary
The protein encoded by this gene is a member of a family of RIM-binding proteins. RIMs are active zone proteins that regulate neurotransmitter release. This gene has been found fused to the receptor-type tyrosine kinase gene RET by gene rearrangement due to the translocation t(10;12)(q11;p13) in thyroid papillary carcinoma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Gene Name: ELKS/RAB6-interacting/CAST Family Member 1
Chromosome: CHR12: 1100403 -1605099
Locus: 12p13.33
ADIPOR2 Gene Summary
The adiponectin receptors, ADIPOR1 (MIM 607945) and ADIPOR2, serve as receptors for globular and full-length adiponectin (MIM 605441) and mediate increased AMPK (see MIM 602739) and PPAR-alpha (PPARA; MIM 170998) ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin (Yamauchi et al., 2003 [PubMed 12802337]).[supplied by OMIM, Mar 2008]
Gene Name: Adiponectin Receptor 2
Chromosome: CHR12: 1800246 -1897845
Locus: 12p13.33
Gene Diseases
The ADIPOR2 ERC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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