ADSS-BPNT1 Fusion FISH Probe
The ADSS-BPNT1 Fusion FISH Probe is used to confirm a fusion of the ADSS and BPNT1 genes. The fusion of the ADSS and BPNT1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| ADSS-BPNT1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-RERE | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-REOR | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-REGO | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-REGR | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-REAQ | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-ORRE | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-OROR | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-ORGO | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-ORAQ | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-GORE | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-GOOR | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-GOGO | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-GOGR | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-GOAQ | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-GRRE | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-GROR | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-GRGO | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-GRGR | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-GRAQ | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-AQRE | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-AQOR | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-AQGO | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-AQGR | 20 (40 μL) | 200 μL |
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| ADSS-BPNT1-20-AQAQ | 20 (40 μL) | 200 μL |
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ADSS Gene Summary
This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010]
Gene Name: Adenylosuccinate Synthase
Chromosome: CHR1: 244571793 -244615436
Locus: 1q44
BPNT1 Gene Summary
BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase's physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity. [provided by RefSeq, Jul 2008]
Gene Name: 3'(2'), 5'-bisphosphate Nucleotidase 1
Chromosome: CHR1: 220230823 -220263191
Locus: 1q41
Gene Diseases
The ADSS BPNT1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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