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AGAP1-AANAT Fusion FISH Probe

The AGAP1-AANAT Fusion FISH Probe is used to confirm a fusion of the AGAP1 and AANAT genes. The fusion of the AGAP1 and AANAT genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AGAP1-AANAT-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AGAP1-AANAT-20-RERE 20 (40 μL) 200 μL
AGAP1-AANAT-20-REOR 20 (40 μL) 200 μL
AGAP1-AANAT-20-REGO 20 (40 μL) 200 μL
AGAP1-AANAT-20-REGR 20 (40 μL) 200 μL
AGAP1-AANAT-20-REAQ 20 (40 μL) 200 μL
AGAP1-AANAT-20-ORRE 20 (40 μL) 200 μL
AGAP1-AANAT-20-OROR 20 (40 μL) 200 μL
AGAP1-AANAT-20-ORGO 20 (40 μL) 200 μL
AGAP1-AANAT-20-ORAQ 20 (40 μL) 200 μL
AGAP1-AANAT-20-GORE 20 (40 μL) 200 μL
AGAP1-AANAT-20-GOOR 20 (40 μL) 200 μL
AGAP1-AANAT-20-GOGO 20 (40 μL) 200 μL
AGAP1-AANAT-20-GOGR 20 (40 μL) 200 μL
AGAP1-AANAT-20-GOAQ 20 (40 μL) 200 μL
AGAP1-AANAT-20-GRRE 20 (40 μL) 200 μL
AGAP1-AANAT-20-GROR 20 (40 μL) 200 μL
AGAP1-AANAT-20-GRGO 20 (40 μL) 200 μL
AGAP1-AANAT-20-GRGR 20 (40 μL) 200 μL
AGAP1-AANAT-20-GRAQ 20 (40 μL) 200 μL
AGAP1-AANAT-20-AQRE 20 (40 μL) 200 μL
AGAP1-AANAT-20-AQOR 20 (40 μL) 200 μL
AGAP1-AANAT-20-AQGO 20 (40 μL) 200 μL
AGAP1-AANAT-20-AQGR 20 (40 μL) 200 μL
AGAP1-AANAT-20-AQAQ 20 (40 μL) 200 μL

AANAT Gene Summary

The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Gene Name: Aralkylamine N-acetyltransferase

Chromosome: CHR17: 74449432 -74466199

Locus: 17q25.1

AGAP1 Gene Summary

This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Gene Name: ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 1

Chromosome: CHR2: 236402735 -237034120

Locus: 2q37.2

Gene Diseases

The AGAP1 AANAT Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.