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AGAP1-ATG4B Fusion FISH Probe

The AGAP1-ATG4B Fusion FISH Probe is used to confirm a fusion of the AGAP1 and ATG4B genes. The fusion of the AGAP1 and ATG4B genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
AGAP1-ATG4B-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
AGAP1-ATG4B-20-RERE 20 (40 μL) 200 μL
AGAP1-ATG4B-20-REOR 20 (40 μL) 200 μL
AGAP1-ATG4B-20-REGO 20 (40 μL) 200 μL
AGAP1-ATG4B-20-REGR 20 (40 μL) 200 μL
AGAP1-ATG4B-20-REAQ 20 (40 μL) 200 μL
AGAP1-ATG4B-20-ORRE 20 (40 μL) 200 μL
AGAP1-ATG4B-20-OROR 20 (40 μL) 200 μL
AGAP1-ATG4B-20-ORGO 20 (40 μL) 200 μL
AGAP1-ATG4B-20-ORAQ 20 (40 μL) 200 μL
AGAP1-ATG4B-20-GORE 20 (40 μL) 200 μL
AGAP1-ATG4B-20-GOOR 20 (40 μL) 200 μL
AGAP1-ATG4B-20-GOGO 20 (40 μL) 200 μL
AGAP1-ATG4B-20-GOGR 20 (40 μL) 200 μL
AGAP1-ATG4B-20-GOAQ 20 (40 μL) 200 μL
AGAP1-ATG4B-20-GRRE 20 (40 μL) 200 μL
AGAP1-ATG4B-20-GROR 20 (40 μL) 200 μL
AGAP1-ATG4B-20-GRGO 20 (40 μL) 200 μL
AGAP1-ATG4B-20-GRGR 20 (40 μL) 200 μL
AGAP1-ATG4B-20-GRAQ 20 (40 μL) 200 μL
AGAP1-ATG4B-20-AQRE 20 (40 μL) 200 μL
AGAP1-ATG4B-20-AQOR 20 (40 μL) 200 μL
AGAP1-ATG4B-20-AQGO 20 (40 μL) 200 μL
AGAP1-ATG4B-20-AQGR 20 (40 μL) 200 μL
AGAP1-ATG4B-20-AQAQ 20 (40 μL) 200 μL

ATG4B Gene Summary

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Gene Name: Autophagy Related 4B Cysteine Peptidase

Chromosome: CHR2: 242577026 -242613271

Locus: 2q37.3

AGAP1 Gene Summary

This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Gene Name: ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 1

Chromosome: CHR2: 236402735 -237034120

Locus: 2q37.2

Gene Diseases

The AGAP1 ATG4B Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.