AGAP1-USP40 Fusion FISH Probe
The AGAP1-USP40 Fusion FISH Probe is used to confirm a fusion of the AGAP1 and USP40 genes. The fusion of the AGAP1 and USP40 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| AGAP1-USP40-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-RERE | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-REOR | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-REGO | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-REGR | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-REAQ | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-ORRE | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-OROR | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-ORGO | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-ORAQ | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-GORE | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-GOOR | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-GOGO | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-GOGR | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-GOAQ | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-GRRE | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-GROR | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-GRGO | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-GRGR | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-GRAQ | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-AQRE | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-AQOR | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-AQGO | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-AQGR | 20 (40 μL) | 200 μL |
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| AGAP1-USP40-20-AQAQ | 20 (40 μL) | 200 μL |
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USP40 Gene Summary
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]
Gene Name: Ubiquitin Specific Peptidase 40
Chromosome: CHR2: 234384164 -234474236
Locus: 2q37.1
AGAP1 Gene Summary
This gene encodes a member of an ADP-ribosylation factor GTPase-activating protein family involved in membrane trafficking and cytoskeleton dynamics. This gene functions as a direct regulator of the adaptor-related protein complex 3 on endosomes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 1
Chromosome: CHR2: 236402735 -237034120
Locus: 2q37.2
Gene Diseases
The AGAP1 USP40 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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