AGAP2-CNOT2 Fusion FISH Probe
The AGAP2-CNOT2 Fusion FISH Probe is used to confirm a fusion of the AGAP2 and CNOT2 genes. The fusion of the AGAP2 and CNOT2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| AGAP2-CNOT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| AGAP2-CNOT2-20-AQAQ | 20 (40 μL) | 200 μL |
|
CNOT2 Gene Summary
This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
Gene Name: CCR4-NOT Transcription Complex Subunit 2
Chromosome: CHR12: 70636773 -70748773
Locus: 12q15
AGAP2 Gene Summary
The protein encoded by this gene belongs to the centaurin gamma-like family. It mediates anti-apoptotic effects of nerve growth factor by activating nuclear phosphoinositide 3-kinase. It is overexpressed in cancer cells, and promotes cancer cell invasion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Aug 2011]
Gene Name: ArfGAP With GTPase Domain, Ankyrin Repeat And PH Domain 2
Chromosome: CHR12: 58118075 -58135944
Locus: 12q14.1
Gene Diseases
The AGAP2 CNOT2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|